The latest figures have been released.
1,095 new Covid-19 cases have been confirmed, as well as five further deaths.
There are 232 confirmed cases in hospitals across the country, while 30 cases are confirmed to be in the ICU.
246 of Wednesday’s cases are in Dublin, with 185 in Meath, 128 in Cavan, 118 in Cork and 63 in Kildare.
The remaining 342 cases are spread across all remaining counties.
529 of the cases are men, while 552 are women. 70% are under 45 years of age, and the median age is 31-years-old.
Speaking about Wednesday’s figures, Tony Holohan said: “Today, we again report a daily new confirmed case figure over 1,000. This situation is extremely concerning. Every single one of us has a role to play.
“We each need to reduce contact with other people as much as possible, so that means staying at home, working from home where possible, practising physical distancing and stopping discretionary socialising.”
Deputy Chief Medical Officer Dr Ronan Glynn said: “People must now make choices. Stop meeting up in groups, stop socialising, stop organising play dates, parties and other social activities.
“People must recognise that the disease is a direct threat to themselves and their families. Now is the time for each of us to act.”
Earlier in the day, Northern Ireland reported 1,217 new cases of Covid-19, as well as four Covid-related deaths.
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