The seizures took place across three separate counties.
Five people have been arrested following separate drug seizures across Connacht on Friday.
Gardaí seized an estimated €289,000 worth of cannabis (pending analysis) and made five arrests following searches across four different locations in Roscommon, Mayo and Sligo on Friday 14 February.
The searches are part of an ongoing investigation into the sale and supply of cannabis in the Roscommon and Leitrim region.
Two searches were carried out at separate locations in Ballaghaderreen in Roscommon.
The first of these searches led to the discovery of 67 cannabis plants and cannabis herb with a value of €54,000. Two men, 33-years-old and 46-years-old were arrested in connection to this seizure.
At a second location, 86 cannabis plants were discovered along with approximately 2kg of cannabis. The total value of the seizure is estimated at €107,000. Following this, a 41-year-old man was arrested.
In Charlestown, Mayo, 80 cannabis plants were seized, with a potential value of €64,000. A 26-year-old man was arrested at the scene.
A fourth search in Clogherevagh, Sligo led Gardaí to the discovery of 80 cannabis plants with a potential value of €64,000. A 49-year-old man was arrested at the scene.
Gardaí have said that all prisoners remain in custody and investigations are ongoing.
