Multiple injuries reported as large cargo plane crashes at US airport

The cargo plane reportedly crashed on take off

The airport in Louisville, Kentucky, has said on X that it is closed after an "aircraft incident".

Flight tracking app Flightradar24 disclosed more information about the plane in a post on X.

It read: "5X2976 was operated by an MD-11(F) registered N259UP. The 34 year old aircraft was converted to cargo and began operations with UPS in 2006."

The plane was destined for Honolulu in Hawaii.

Injuries have been reported at the scene, the Louisville Metro Police Department says.

UPS are aware of the incident and have confirmed three crew members were onboard.

Social media has been flooded with videos showing the crash as well as the aftermath.

One of the tamer videos shows cars backed up on a motorway as thick, black smoke fills the air.

Warning: The following videos contains distressing images.

A video of the plane crash appears to show the MD-11F on fire as it rotates on the runway to take off.

Authorities say the plane was carrying around 25,000 gallons of fuel.

It was set for an around eight-hour flight to Hawaii, meaning it would've been carrying lots of fuel, as reflected in the fireball that ensued the incident.

This is a breaking news story. More to follow.